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By Mary Anne Dunkin | May 21, 2021 When joint pain in the hands makes it difficult to maintain daily activities, your doctors first advice will likely include activity modification that, is avoiding activities that cause or worsen pain as well as splints or braces to stabilize and support the painful joints, pain-relieving gels or rubs, or acetaminophen or nonsteroidal anti-inflammatory drug (NSAIDs) pills or capsules