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In addition, the activation of ARE induces the activation of NAD(P)H quinone oxidoreductase-1 (NQO1) and heme oxygenase-1 (HMOX1), which further enhances the antioxidant capacity [65]

doi: 10.3389/fimmu.2026.1797949 Received 28 January 2026 Revised 30 March 2026 Accepted 08 April 2026 Published 30 April 2026 Volume 17 - 2026 Edited by Pamela Valva, General Hospital of Children Ricardo Gutierrez, Argentina Reviewed by Pedro Miguel Rodrigues, Biodonostia Health Research Institute (IIS Biodonostia), Spain Felix Wensveen, University of Rijeka, Croatia Updates Copyright 2026 Gonzlez-Serrano, Onoiu, Jimnez-Franco, Cambra-Corts, Camps and Joven

Naturally occurring cannabinoids and their role in modulation of cardiovascular health

The ideal BPC 157 dosage typically ranges from 200-500 mcg per day, with athletes sometimes using up to 800 mcg

In vivo studies in rats demonstrated no hemolysis, platelet aggregation, or acute toxicity, confirming the biocompatibility of the polymeric NPs