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Redox regulation of inflammatory processes is enzymatically controlled

Luo H, Wang X, Wang J, Chen C, Wang N, Xu Z, et al

In particular, brain organoids are revolutionizing the study of mitochondrial-based neurological diseases since they are organ-specific and model-generated from a patients cell, thereby overcoming some of the limitations of traditional animal and cell models

Consistently, KGA-WT overexpression significantly reduced the elevated levels of lipid ROS triggered by KGA interference, whereas KGA-MUT alone did not offer such an effect (Fig