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The molecular origin for the more selective binding of ether analogues to this target was elucidated by crystallography

J Endocrinol 2006

Cardiovasc Res 121 , 7796 (2025)

In an acute graft-versus-host disease model, specific deletion of XBP1 in intestinal epithelial cells leads to dysregulation of ERS signaling and exacerbates tissue damage