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A proposed dual role of neuromelanin in the pathogenesis of Parkinson's disease

Lower baseline CSF -synuclein levels in the DATATOP study predicted a better preservation of cognitive function in early PD patients with up to 8 years of follow-up (Stewart et al., 2014)

Despite being extensively studied, current pharmacological and surgical interventions remain mostly symptomatic, leaving limited efficacy in halting or reversing disease progression

Pueraria lobata (Kudzu) Pueraria lobata, or kudzu root, contains isoflavones such as puerarin and daidzin that modulate hypothalamic-pituitary signaling, vascular tone, and renal perfusion

Common in Hashimotos due to comorbid celiac disease, autoimmune gastritis, or menstrual blood loss