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At the epigenetic level, MenSCs restore the expression of TET1/2 and 5-hmC levels in hepatocellular carcinoma cells in a time-dependent manner

933 These results suggest that PPM1K mediates the disturbance of BCAA metabolism, regulates cerebral I/R injury by activating neuronal ferroptosis, and may serve as a therapeutic intervention target

Interestingly, CBS is upregulated by transcription factors such as nuclear factor erythroid 2-related factor 2 (NRF2) 17 , SP1/3 18 , and NFY 18 and its upregulation confers resistance against ferroptosis in ovarian cancer cells 17