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Description

Immunometabolic adaptation of CD19-targeted CAR T cells in the central nervous system microenvironment of patients promotes memory development

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PLoS One 9:e85637 Zhang Y, Wang B, Liang Q, Qiao L, Xu B, Zhang H, Yang S, Chen J, Guo H, Wu J, Chen D (2015) Mitochondrial DNA D-loop AG/TC transition mutation in cortical neurons of mice after long-term exposure to nucleoside analogues

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Other noteworthy effects include those of SeMet which can increase SelS and GPx1 expression in splenocytes, as well as antioxidant capacity, to reduce immunotoxicity caused by AFB1, with GPX maintaining ROS balance by removing excess hydroperoxides (141)

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The robustness of the GI tract can be attributed to a number of factors, including the rapid and efficient repair of the GI epithelium within hours, rapid turnover of the epithelial lining in 45 days, and dilution effects in the aqueous GI contents

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