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I think some people could benefit from higher doses, up to 3600mg per day, but this has not yet been studied in a controlled manner

Cheng C, Zhang W, Zhang C, Ji P, Wu X, Sha Z, et al

(2020) Comparison of the effect of clarithromycin triple therapy with or without N-acetylcysteine in the eradication of Helicobacter pylori : a randomized controlled trial

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A key player in this process is the nuclear factor erythroid 2-related factor 2(Nrf2)Kelch-like ECH-associated protein 1 (Keap1) pathway, which regulates the antioxidant defense mechanisms of tumor cells (Torrente and DeNicola 2022)