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Description

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Increased matrix stiffness also promotes VEGFR-2 internalization, which then causes ERK phosphorylation and cell proliferation ( c-SRC Pathway Another mechanotransductive protein downstream of VEGFR-2 signaling is Src, known as c-Src in humans, which is a cytoplasmic tyrosine kinase associated with the cell membrane or endosomal membranes

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