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NF-B, MAPK, and PKC- signaling pathway activity was assessed, alongside Hsp72, Hsp90-, and TLR4 expression and levels of apoptosis

Certain metals trigger fibrillation of methionine-oxidized -synuclein

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For example, introducing exogenous mRNA into parent cells can be packaged into EVs and then delivered to target cells to induce specific gene expression (Zomer et al., 2015