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The conformational change in the sensory domain is involved in the detection of the target metabolite through the genetically encoded FRET-based sensor (a tandemly fused protein)

Statistics and reproducibility All statistics were calculated using GraphPad Prism version 9 with appropriate tests described in the figure legends

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As is obvious from comparing the data of Tables 1 and 2 with those of 3, the diffusion coefficients in a gaseous and a liquid phases differ by a factor of 10 4 10 5 , which is quite reasonable considering that diffusion is the movement of individual molecules through the layer of molecules of the same substance (self-diffusion) or other substances (binary diffusion in which the molecules of two substances interdiffuse)

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