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During development and progression of atherosclerosis, Nrf2 signaling modulates many physiological and pathophysiological processes, like regulation of lipid homeostasis, CD36 gene expression regulation, foam cell formation, macrophage polarization, immunity regulation (Th2 differentiation and inhibition of pro-inflammatory gene expression through NFB down-regulation), redox regulation and inflammation, improvement of endothelial dysfunction, as well as GSH synthesis and utilization (234245)

Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis

PDAs: polydopamines

Beyond its anti-inflammatory and antioxidant properties, EGCG modulates key signaling pathways that regulate neuronal survival

When used in combination with healthy living practices, they can improve weight loss by speeding up fat loss through a healthy metabolism