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doi: 10.1016/j.autrev.2021.102845

These results suggest that mediator localizes to gene regions to recruit condensin via the Cnd1-Pmc4 interaction

The ongoing clinical trials of oral SERDs primarily focus on identifying subpopulations with potential benefits following CDK4/6 inhibitor failure, investigating the efficacy of SERDs in combination with CDK4/6 inhibitors as first-line therapy, and reducing mortality rates among high-risk populations during the adjuvant stage