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For instance, microRNAs functioning as cancer inhibitors have demonstrated the capability to exert anti-cancer effects in vivo through sEVs

The miR-23a27a24-2 cluster plays a critical role in promoting the inflammatory polarization of macrophages, particularly influencing the balance between pro-inflammatory (M1) and anti-inflammatory (M2) states in the context of ovarian cancer

In addition, deleting a-synuclein or ACSL4 in LUHMES cells, neuronal precursor cells, resulted in a robust reduction in ePE and ePC levels regardless of fatty acid chain species 138

doi: 10.1038/nrn1434 160 BandookwalaMSenguptaP

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