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Pigmentation from amodiaquine simulating cyanosis

10.3390/ijms20184472

Genetic knockout of solute carrier 22A member 4 (SLC22A4), part of the large solute carrier 22A (SLC22A) family, in both mice (Reference Kato, Kubo and Iwata25) and zebrafish (Reference Pfeiffer, Bach and Bauer26) , resulted in dramatic reduction of ergothioneine to undetectable concentrations in many tissues (e.g