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19,20 In a 2013 systematic literature review, ALC, alpha lipoic acid, calcium, glutamine, glutathione, magnesium-acetylcysteine, omega-3 fatty acids, vitamin B 6 , and vitamin E were evaluated from a pool of 24 studies to determine their individual efficacies in the treatment of CIPN

Funding The authors extend their appreciation to the Deanship of Scientific Research and Libraries in Princess Nourah bint Abdulrahman University for funding this research work through the Research Group project, Grant No

In diagnostics, cancerous tissue biopsy is the optimal choice for subtyping and grading cancers

Studies have shown that people can have high or normal B12 levels in the blood and actually show virtually no B12 in the spinal fluid, meaning the B12 is not being transported from the blood stream into the cells where it should be absorbed and used

Serotonin and oxytocin which are vital in the development of neural connectivity, are fuelled by glucose transporters GLUT3, whose sufficiency is crucial (Ye et al., 2021)