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Marginal deficiency Although frank vitamin E deficiency is rare, marginal intake of vitamin E may be relatively common

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Ceramides as bioactive lipid species affect mitochondria function by several mechanism including changes in membrane chemical composition, inhibition of the respiratory chain, ROS overproduction and oxidative stress, and also by activating mitophagy

Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2

In clinical practice, these mechanistically dissimilar antidepressants likely both target monoamine pathways, as most available antidepressants target monoamines [21]