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Three primary ionotropic glutamate, NMDA, alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionate (AMPA), and kainate receptors [92], can trigger excitotoxic cascades

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Neuropsychopharmacology 37:338349 Garzn J, Rodrguez-Muoz M, Snchez-Blzquez P (2012) Direct association of Mu-opioid and NMDA glutamate receptors supports their cross-regulation: molecular implications for opioid tolerance