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Therefore, introducing drug development technologies, such as computer-aided drug design, high-throughput screening, systems modeling and simulation to obtain derivatives of AS-IV with increased bioavailability and conducting targeted validation or further adopting biocompatible drug carriers, such as nanoparticles, liposomes and micelles encapsulating AS-IV, may be required to achieve its efficient delivery

All these results advocate ROS species as tumor-suppressive agents and the role of antioxidants in cell growth and survival of cancer cells (Chio and Tuveson 2017)

Compared to conventional imaging probes in the visible region, fluorescence imaging in the NIR-II region (10001700 nm) exhibits deeper tissue penetration and higher spatiotemporal resolution due to reduced tissue autofluorescence and photon scatter, enhancing accuracy and reliability in disease detection [13], [14], [15], [16], [17], [18]

Betarbet R, Greenamyre JT (1999)

Multi-modality Therapy For Stage IIIa N2 Non-small Cell Lung Cancer: Does The Answer Lie In The Components