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In contrast to zinc deficiency that affects these three aspects of physiology, impaired growth and development is associated with magnesium deficiency [35], selenium, iron, and magnesium deficiencies are related to impaired immune function [32, 36,37,38,39,40], and copper, magnesium, and manganese have important functions in regulation of blood sugar [3, 41]

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The risk increases if these agents are used alongside insulin or sulphonylureas