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It is dosed only once a week, which makes it easier for patients to stay on therapy

In addition to the traditional perforingranzyme and FasFas ligand cell death induction pathways, interferon- secreted by CD8+ T cells activated in antiPD-L1 therapy can down-regulate System X c expression to reduce cystine uptake and induce ferroptosis (152)

Cancer-associated mutation and beyond: the emerging biology of isocitrate dehydrogenases in human disease

The quantitative analytical findings of Caspase-3 immunoreactivity, represented as a percentage across all groups, are shown in Fig

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