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evidence for brain influx through store-operated calcium channels

In 2006, biochemical and spectroscopic analyses indicated that XPD coordinates a 4Fe4S cluster, which is a key determinant of XPD helicase activity

In PD patient brain tissue and cellular models of PD, S-nitrosylation of peroxiredoxin (PrxII) decreases peroxidase activity causing H 2 O 2 to accumulate, exasperating oxidative stress 82

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