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Additionally, decreased expression of Sequestosome 1 (SQSTM1) in diabetic keratinocytes impairs autophagy-lysosome-mediated degradation of ACSL4, and increasing ACSL4 expression could drive ferroptosis [48]

Bioeng Transl Med 9(6):e10680 Zhuang Y, Zhao L, Zheng L, Hu Y, Ding L, Li X et al (2017) LAPONITE-Polyethylenimine based theranostic nanoplatform for tumor-targeting CT imaging and chemotherapy

10.1002/med.21981 203

Some research has indicated that l-arginine is worth investigating as a migraine treatment since it helps dilate blood vessels

163 As an example, Tiriveedhi et al reported that lung transplant patients, who developed chronic lung allograft rejection, show increased defensin and decreased serum AAT levels along with high concentrations of AAT-defensin complexes in their bronchial lavage