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Psychiatric hospitalization was defined as the presence of a medical claim for an inpatient admission with a diagnosis code of a psychiatric disorder (International Classification of Diseases, 9th Revision [ICD-9] codes 290314 or International Classification of Diseases, 10th Revision [ICD-10] codes F00-F99) in the primary or secondary position

Retesting of senolytic compounds in SK-MEL-103 cells SK-MEL-103 cells were used to assess the senolytic activity of the hits discovered in the primary screening

Since deficits in glutathione have been linked to psychosis and schizophrenia, the team explained, chemical agents capable of restoring the balance in the brain between glutathione and glutamate may provide therapeutic benefit

Though unlikely with typical product concentrations that fall within safe parameters, awareness of this risk remains important

Quantification of the fluorescence emission by area Perimeters were drawn around the nuclei following the area marked with Hoechst, and the mean of nuclear CMFDA fluorescence was obtained (100 cells per condition in 3 separate experiments)