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Description

Anesthesiology 110:11391157

Aug 15 2010;82(4):361-8, 369

Alteration in the formation of the cornified envelope caused by genetic mutations (e.g., filaggrin), lipid profiles, immune dysregulation, or environmental factors (e.g., protease-active allergens and pathogens) can result in skin barrier dysfunction and AD onset 20,21,22,23