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After removing duplicates, eleven observational and cohort studies fulfilled all eligibility criteria and were considered for the present review

You have a known copper allergy or a history of allergic dermatitis to copper-containing jewelry or cookware

Disbalanced nutrition and excessive physical activity can provoke the development of dysbacteriosis and increase intestinal permeability which can potentially lead to a pro-inflammatory response

doi: 10.1016/j.jep.2020.112876 9

These examples illustrate both the potential and the limitations of oral glutathione beneficial in some contexts but by no means miracle-cure and the effect is variable