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Fixed-combination brinzolamide 1%/brimonidine 0.2% vs monotherapy with brinzolamide or brimonidine in patients with open-angle glaucoma or ocular hypertension: results of a pooled analysis of two phase 3 studies

Male SD rats and healthy human volunteers were randomly divided into four groups: CAF, RHO, CAF + RHO, and a control group (CTR)

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Purkinje cells, dorsal column neurons, and cardiomyocytes all exhibit ferroptotic features in FRDA, yet this study does not distinguish pathway differences across organsfor example, whether cerebellar injury depends more on ACSL4-mediated lipid dysregulation and whether cardiomyocyte vulnerability primarily reflects GPX4 inactivation

In a mouse model of allergic rhinitis, treatment with geniposide significantly reduced serum levels of IL-4, IL-5, and IL-17