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894 Acid sphingomyelinase (ASM)-mediated autophagy activation is critical for hyperglycemia -induced GPX4 degradation, and inhibition of ASM improves osteogenic function by reducing hyperglycemia-induced GPX4 degradation and subsequent ferroptosis

Science 345 , 10211026 (2014)

The ABCDE rule encompasses visual characteristics such as color, shape, texture, and diameter, which have been utilized in several studies to extract features of skin lesions 6,7,8

Chemotherapy-induced cardiotoxicity

Mild to moderate toxicity occurs with peak salicylate concentration in the range 3580 mg/dl (300800 mg/L) whilst peak levels greater than 80 mg/dl (800 mg/ml) are associated with severe toxicity