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More recently, a survey on the immune profile of people at the first episode of major depression documented a significant activation of immune circuit Th1 compared to the control group, with an increase in inflammatory cytokines such as TNF and IL-6 and also several chemokines [83]

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Evidence at present favours chronic inflammation as a trigger for chronic insulin insensitivity, rather than the reverse situation.

Includes selenium to support antioxidant enzymes