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In addition to the limited antioxidant defenses present in the nuclear region of the lens, another factor that could contribute to the susceptibility of this area of the lens to cataract may be the loss of -crystallin, 38 a major structural protein of the lens

subject: F (21,42) = 0.9645, p = 0.5209)

D'AgostinoVCaranciFNegroAPiscitelliVTuccilloBFasanoFet al

Overall, this work provides a comprehensive understanding of CRC metabolic reprogramming and its microenvironmental impacts, offering critical insights to guide the development of novel metabolism-targeted therapeutic strategies for CRC

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