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Excessive ionophore administration can overwhelm these defenses, leading to systemic copper poisoning, characterized by hepatotoxicity, nephrotoxicity, and hematopoietic suppression [239]

Peptide therapy can boost energy levels and enhance physical performance, making it ideal for athletes and individuals with demanding lifestyles

Conversely, deubiquitinases/DUBs remove ubiquitin chains from substrate proteins, counteracting the activity of E3 ligases, thereby stabilizing the targeted proteins

The activity of the antioxidant enzyme GPx was determined by standard protocols, in blood samples (2 ml each), collected from all subjects, after the onset of arrhythmia (for groups I and II), by venipuncture (in K2EDTA vacutainers), using a standardized Ransel Laboratory kit (RandoxLaboratories, Ltd.)