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Trends Cell Biol 26(3):165176 Yang W, Wang Y, Zhang C, Huang Y, Yu J, Shi L, Zhang P et al (2022a) Maresin1 Protect Against Ferroptosis-Induced Liver Injury Through ROS Inhibition and Nrf2/HO-1/GPX4 Activation

Direct and indirect cost of urea excretion

Microbes can play a direct role in the activation and inactivation of drugs via biotransformation of drug molecules into secondary metabolites (Enright et al., 2016)

doi: 10.3390/ph16091216 79 GargusM.Ben-AzuB.LandwehrA.DunnJ.ErricoJ

(2000) Platelet-derived growth factor rapidly increases activity and cell surface expression of the EAAC1 subtype of glutamate transporter through activation of phosphatidylinositol 3-kinase