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Raschi E, Gatti M, and Gelsomino F, et al (2020) Lessons to be learnt from real-world studies on immune-related adverse events with checkpoint inhibitors: a clinical perspective from pharmacovigilance Target Oncol 15 (4) 449466 PMID: 32725437 PMCID: 7434791 17

In contrast to its predominant oxidizing activity in the ER, surface-associated PDI acts primarily as a reductant

Critical limitations identified in the systematic review include predominant use of small rodent models (primarily rats), short follow-up periods relative to human healing timelines, variable dosing regimens complicating dose-response assessment, and lack of standardized outcome measures across studies

Fate of Dispersants Associated with the Deepwater Horizon Oil Spill