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Additionally, it has been suggested that polyphenols ability to bind with bile acids and promote their fecal excretion may be the mechanism by which they lower plasma cholesterol levels [122]

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84 For instance, when the ROS level increased and induced oxidative stress in mouse myocardium, the expression of Mfn1 and Mfn2 decreased, and smaller and fragmented mitochondria appeared in mouse cardiomyocytes, representing that oxidative stress pushed mitochondrial dynamics to the direction of fission