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This review is to accelerate the development of novel natural and herbal medicine treatments and to offer novel perspectives on how to treat ferroptosis in stroke

However, the clinical benefit of this modality has still been limited due to several defects such as adverse events, acquired drug resistance, tumor recurrence, and lack of validated biomarkers, which impel further research on mechanisms of tumor angiogenesis, the development of multiple drugs and the combination therapy to figure out how to improve the therapeutic efficacy

In AA, various intrinsic and extrinsic environment triggers (e.g., physical/emotional stress, viral infections, and trauma) initiate a pathological cascade [16]: autoreactive CD8 + T cells infiltrate around the hair follicle and secrete excessive amount of IFN-, a key inducer of hair follicle IP collapse [22]

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