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326 In addition, the role of arginine methyltransferase (PRMT) in the regulation of tumorigenesis and development has also received extensive attention, and a variety of PRMT inhibitors have shown good anti-tumor activity in vitro and animal models, and a variety of drugs targeting type I PRMT and PRMT5 have been tested

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Response to Excessive and Reduced Stimulation of Receptors: Excessive Receptor Activation can result in desensitization or down regulation