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References: Babu MM, Luscombe NM, Aravind L, Gerstein M, Teichmann SA

10.1016/j.atherosclerosis.2013.10.029 Atherosclerosis 98 RousselJ.ThireauJ.BrennerC.SaintN.ScheuermannV.LacampagneA.et al (2015)

Many enzymes require zinc to maintain their structure and catalytic activity

Ramucirumab plus erlotinib in patients with untreated, EGFR -mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial