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By donating electrons or hydrogen atoms, curcumin can terminate free radical chain reactions, thus protecting cellular lipids, proteins, and DNA from oxidative damage ( Across oral and periodontal models, curcumin activates cytoprotective antioxidant pathways (e.g., Nrf2/HO-1) and restores redox balance, limiting downstream tissue injury

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Next, the activated NF-B heterodimer translocates to the nucleus, promoting the transcription of pro-inflammatory genes [73], particularly, the genes that control apoptosis, causing the production of cytokines and interferons that regulate inflammatory responses

Compared to NHW with MASLD, the risk of cirrhosis was significantly higher among Hispanics (5.0 vs