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This protects myofibroblasts from apoptosis, thereby feeding the de novo glycine synthesis needed for myofibroblasts collagen production and deposition

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One of the strategies for the treatment of RA is to convert traditional Treg cells into Foxp3 + Treg cells with stable inhibitory function, and reduce the related inflammation caused by the conversion of Treg cells into Th17 cells (199, 200)