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In another report, it was shown that K48-linked ubiquitinated cGAS is directly sequestered into the lysosome for degradation by interacting with the selective autophagy receptor p62 ( Figure 3 )

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Reintroduction of XKR8 reinstated PS exposure in XKR8 KO HL-60 cells during apoptosis and PMA-induced NET formation and successfully rescued NET formation (Fig

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