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The mighty mitochondria

Pietruski P, Paskal W, Paluch , Paskal AM, Nitek , Wodarski P, Walecki J, Noszczyk B

( c ) Heatmaps and summary bar charts of metabolic gene expression patterns of genes from ( b )

Some studies have suggested that increased ferroptosis may compromise the efficacy of PD-L1 immunotherapy, while inhibiting ferroptosis remodels the immunosuppressive microenvironment and enhances the effectiveness of immunotherapy (74)

The activation of the IL-17 signaling pathway triggers multiple pathological changes, including stratum corneum thickening, epidermal layer abnormalities, and keratinocyte apoptosis, ultimately leading to inflammatory factor release and solar dermatitis development [27, 28]