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Senescent fibroblasts drive ageing pigmentation: a potential therapeutic target for senile lentigo

Fabio Hecht is a Postdoctoral Scholar at the University of Rochester

Biological Activities Antioxidant activity Glutathione Low cellular concentrations of glutathione, a major intracellular antioxidant, and/or overproduction of reactive oxygen species (ROS) can lead to oxidative stress-induced damage to biological macromolecules and contribute to the development and progression of pathological conditions

Enzyme cloning The GUS genes from Lactobacillus rhamnosus and Ruminococcus gnavus were purchased from Bio Basic in the pUC57 vector

This approach also enables to complement the findings on d-monobody selectivity described above and to determine its interactome