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[30] For example, cyanocobalamin can be converted to its analog cobalamins via reduction to B 12s , followed by the addition of the corresponding alkyl halides, acyl halides, alkene or alkyne

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7 Limitations When interpreting the findings of this review, several limitations must be acknowledged

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Secondly, the redox status of the cell affects many of the enzymes in one-carbon metabolism including MATI, MATIII, MS, BHMT, as well as CBS and GCS in the transsulfuration pathway, and therefore one cannot evaluate GSH metabolism without including the methionine and folate cycles