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Another genome-wide meta-analysis on data from European and Chinese populations (84,694 individuals) also found the ACSL5 -ZDHHC6 locus is associated with ALS and links weight loss to the disease geneticsbody weight loss is a frequent complication in ALS patients and is reported to be associated with shorter survival ( ACSL5 and ALS was also confirmed by Nakamura et al

doi:10.1517/13543776.2016.1102888 fda, cder

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The superoxide radical O 2 is produced by numerous biochemically relevant redox processes and is thought to play role in diseases and pathological processes, such as aging, cancer, membrane or DNA damage, etc