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Aust J Gen Pract 48(8):516519 Rhee MK et al (2024) Bacterial keratitis preferred practice Pattern

Some eventually become valuable therapies, while others do not

Bioinformatics 40 , btae069 (2024)

Upregulation or modulation of genes involved in the ergosterol biosynthetic pathway (ERG family), as well as modifications to sterol content, may alter the binding or activity of polyenes, and in the case of azoles, change the abundance of the target enzyme (lanosterol 14-demethylase), which affects its activity