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10.1084/jem.20141656 110 Lappe-SiefkeC.GoebbelsS.GravelM.NickschE.LeeJ.BraunP

Restoring or enhancing neurotrophic signaling may help counteract the detrimental effects of BBB disruption and promote cognitive recovery (Miyake et al., 2020)

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6c and Extended Data Fig

While these types of studies have been shown to be very useful for understanding the pathways involved in acute excitotoxicity, it has proven much more difficult to study chronic excitotoxicity in culture partly because it is not entirely clear how to define chronic in the context of cell culture