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78 While it may be tempting to conclude from these studies that NOX inhibition with celastrol or other drugs may represent an interesting therapeutic goal in COPD, it is important to recall that individuals with genetically defined NOX deficiencies are afflicted by life-threatening bacterial infections

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Certain cell lines showed susceptibility to ferroptosis but without expressing any detectable amounts of major LOX enzyme (Shah et al., 2018)

In non-NAFLD participants, only high MFI, only low MVZ and AMC was observed in 12 (13%), 12 (13%) and 5 (8%), respectively