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140 The role of lncRNAs in cardiovascular disease LncRNAs is a double-edged sword in cardiovascular disease progression, being both a positive regulator and a negative regulator (Table 4)

Other investigations reproduced the acceleration of the disease in animals expressing both wild type and mutant SOD1 but failed to find a correlation between expression of wild type SOD1 and protein aggregation (Prudencio et al., 2009)

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Methodology We performed a MEDLINE/Google scholar/PubMed search using the terms 'drug-induced liver injury,' 'DILI,' and 'hepatotoxicity, Recent findings in DILI, management of DILI' and analyzed recent literature to identify relevant articles